Sex differences in muscle activation patterns associated with anterior cruciate ligament injury during landing and cutting tasks: A systematic review.

Neuromuscular control is critical for maintaining dynamic joint stability and mitigating the risk of anterior cruciate ligament (ACL) injury. Given the increased risk of ACL injury in females, sex-based differential muscle activation strategies are often associated with this risk. For example, the quadriceps-dominant muscle activation strategy sometimes observed in females has been discussed as a cause of their increased risk of ACL injury. However, there has been no synthesised knowledge on sex differences in muscle activation patterns associated with ACL injuries. Therefore, the purpose of this review was to synthesise sex differences in muscle activation patterns in movements associated with ACL injuries in both adult and adolescent populations. A systematic electronic database search was conducted. Thirty studies were included in the review. Females demonstrated higher pre- and post-landing activation of the quadriceps and lower activation of the hamstrings in 15 studies. Females also had higher quadriceps-to-hamstring co-contraction ratios during pre- and post-landing phases compared to their male counterparts in 4 of 9 studies that considered co-contraction. While some studies supported the quadriceps-dominant activation strategies in females, no consensus can be drawn due to methodological inconsistencies and limitations. Also, despite the importance of ACL injury prevention in children and adolescents, the evidence on sex difference in muscle activation patterns in this population is insufficient to draw meaningful conclusions.

Effects of an Injury Prevention Program on Anterior Cruciate Ligament Injury Risk Factors in Adolescent Females at Different Stages of Maturation.

The ideal timing to implement anterior cruciate ligament injury prevention programs with respect to maturation is unclear. The purpose of this study was to investigate the effects of an injury prevention program on knee mechanics in early-, late-, and post-pubertal females. In the study, 178 adolescent female basketball players were assigned to six groups: early-pubertal training, early-pubertal control, late-pubertal training, and late-pubertal control, post-pubertal training, and post-pubertal control. The training groups performed an injury prevention program for six months. Medial knee displacement, knee flexion range of motion, and the probability of high knee abduction moment were assessed before and after the training period. After the six-month training period, medial knee displacement was significantly increased in the early-pubertal control group whereas it was unchanged in the early-pubertal training group. Knee flexion range of motion was significantly decreased in the early-pubertal control group whereas it did not change in the early-pubertal training group. The probability of high knee abduction moment was increased in the early-pubertal control group whereas it was unchanged in the earl-pubertal training group. The probability of high knee abduction moment was also decreased in the post-pubertal training group whereas it did not change in the post-pubertal control group. The program limited the development of high-risk movement patterns associated with maturation in early puberty while improving the knee mechanics in post-pubertal adolescents. Therefore, an injury prevention program should be initiated in early puberty and continue through the post-puberty years.

Effect of injury prevention training on knee mechanics in female adolescents during puberty.

PURPOSE/BACKGROUND: Female adolescents change their landing mechanics during puberty. It is unknown whether implementation of anterior cruciate ligament (ACL) injury prevention training reduces the loss of knee control in female athletes during puberty. The purpose of this study was to evaluate the effect of injury prevention training on dynamic knee alignment in female basketball players specifically when the knee mechanics were changing during puberty. METHODS: Sixty female junior high school basketball players participated and were divided into two groups: a training group (n = 32) and a control group (n = 28). The training group underwent an injury prevention program for 6 months, whereas the control group maintained a regular training routine. The knee valgus motion and knee flexion range of motion during a drop vertical jump were measured before and after the training period. The probability of a high knee abduction moment (pKAM) was also evaluated using an ACL injury prediction algorithm. RESULTS: The knee valgus motion was significantly increased in the control group (p < 0.001), whereas it did not change in the training group (p = 0.64). Similarly, the knee flexion range of motion was significantly decreased in the control group (p < 0.001), whereas it was not changed in the training group (p = 0.55). The pKAM was significantly increased in the control group (p < 0.001), but not in the training group (p = 0.06). CONCLUSIONS: Implementation of injury prevention training was effective in limiting the loss of knee control in female athletes during puberty. Lowering the risk of ACL injury might be possible in this population. LEVEL OF EVIDENCE: 2b.